The Journal of Bone and Joint Surgery (American). 2009;91:68-75.
doi:10.2106/JBJS.I.00339
© 2009 The Journal of Bone and Joint Surgery, Inc.
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Amniotic Constriction Band: A Multidisciplinary Assessment of Etiology and Clinical Presentation

Charles A. Goldfarb, MD1, Achara Sathienkijkanchai, MD2 and Nathaniel H. Robin, MD2

1 Department of Orthopaedic Surgery, Washington University School of Medicine, 660 South Euclid Avenue, Campus Box 8233, St. Louis, MO 63110. E-mail address: goldfarbc@wustl.edu
2 Division of Medical Genetics, Department of Pediatrics, University of Alabama at Birmingham, Kaul 210, 1530 3rd Avenue South, Birmingham, AL 35294

The first 150 words of the full text of this article appear below.


   Introduction
 
Amniotic constriction band, first described in 1832 by Montgomery1, is one term used to describe a wide range of associated congenital anomalies, including anular constrictions of multiple extremities, oligodactyly, acrosyndactyly, talipes equinovarus, cleft lip and cleft palate, and hemangiomas. Additional, less common clinical manifestations include complete absence of the limb, short umbilical cord, craniofacial disruptions, neural tube defects, cranial defects, scoliosis, and body-wall defects, such as gastroschisis and extrathoracic heart. Some of these manifestations are uncommonly noted at birth because they result in spontaneous abortion2-5.

The prevalence of amniotic constriction band is approximately one in 1200 to one in 15,000 live births6,7. The prevalence rate for male infants has been reported to be 0.91 and, for female infants, 1.44. These defects are reported to occur 1.76 times more frequently among African-Americans as compared with Caucasians6. Evidence of familial involvement is extremely rare. Although temporal and . . . [Full Text of this Article]


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