The Journal of Bone and Joint Surgery (American). 2009;91:2700-2707.
doi:10.2106/JBJS.H.00924
© 2009 The Journal of Bone and Joint Surgery, Inc.
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Familial Bilateral Osteochondritis Dissecans of the Femoral Head

A Case Series

Mark C. Lee, MD1, Derek M. Kelly, MD2, Daniel J. Sucato, MD, MS2 and John A. Herring, MD2

1 Department of Orthopaedic Surgery, University of Connecticut, Connecticut Children's Medical Center, 282 Washington Street, Hartford, CT 06032. E-mail address: mlee01@ccmckids.org
2 Department of Orthopaedic Surgery, University of Texas at Southwestern Medical Center, Texas Scottish Rite Hospital for Children, 2222 Welborn Street, Dallas, TX 75219

Investigation performed at the Department of Orthopaedic Surgery, University of Texas at Southwestern Medical Center, Texas Scottish Rite Hospital for Children, Dallas, Texas

The first 150 words of the full text of this article appear below.


   Introduction
 
Osteochondritis dissecans is a pathologic fragmentation of a segment of subchondral bone and its overlying cartilage. Although the exact etiology is unclear, one commonly accepted theory is a focal interruption in blood supply to the periarticular bone1. Osteochondritis dissecans lesions are most commonly seen in the distal part of the femur, the distal part of the humerus, and the talus. Involvement of the femoral head is rare and typically is associated with skeletal dysplasias or Legg-Calvé-Perthes disease. Idiopathic osteochondritis dissecans of the femoral head is extremely rare and is typically unilateral2.

We present three cases of bilateral idiopathic femoral head osteochondritis dissecans that occurred in multiple members of the same family over three generations. The pattern of transmission is presented with a pedigree diagram. The patients were informed that data concerning the case would be submitted for publication, and they consented.


   Case Reports
 
CASE 1. In 1981, an eleven-year-old . . . [Full Text of this Article]


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