The Journal of Bone and Joint Surgery (American). 2008;90:90-101.
doi:10.2106/JBJS.H.00633
© 2008 The Journal of Bone and Joint Surgery, Inc.
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Autologous Chondrocyte Implantation in the Knee Joint: Open Compared with Arthroscopic Technique

Comparison at a Minimum Follow-up of Five Years

Alberto Ferruzzi, MD1, Roberto Buda, MD1, Cesare Faldini, MD1, Francesca Vannini, MD1, Francesco Di Caprio, MD1, Deianira Luciani, MD1 and Sandro Giannini, MD1

1 Department of Orthopaedic Surgery, University of Bologna, Istituto Ortopedico Rizzoli, Via G.C. Pupilli 1, Bologna 40136, Italy

The first 150 words of the full text of this article appear below.


   Introduction
 
Autologous chondrocyte implantation is a widely used technique for treating cartilage lesions1-10. The technique, first introduced and described by Brittberg et al. in 199411, required an arthrotomy of the joint, débridement of the lesions, and the suturing of a periosteal flap to create a pocket to host the chondrocytes. Autologous chondrocyte implantation in the knee joint has provided hyaline-like repair tissue11-16, with satisfactory clinical results in 80% to 90% of patients1,7,17. Moreover, autologous chondrocyte implantation has been shown to be a valid alternative to the mosaicplasty and microfracture repair techniques used in the treatment of osteochondral lesions of the knee1,6,13,17-20.

In the recent past, to simplify the autologous chondrocyte implantation surgical technique, a three-dimensional hyaluronic acid scaffold was developed to support the autologous chondrocytes13. This scaffold enables an arthroscopic implantation technique to be used21. Furthermore, the chondrocytes embedded on the hyaluronic acid scaffold . . . [Full Text of this Article]


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