The Journal of Bone and Joint Surgery (American). 2008;90:163-174.
doi:10.2106/JBJS.H.00753
© 2008 The Journal of Bone and Joint Surgery, Inc.
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Antibiotic Cement-Coated Nails for the Treatment of Infected Nonunions and Segmental Bone Defects

Raghuram Thonse, MS(Orth), DNB(Orth), FRCS(Glasg), FRCS(Ed)1 and Janet D. Conway, MD2

1 Musgrave Park Hospital, Belfast BT9 7JB, United Kingdom. E-mail address: thonser@yahoo.co.uk
2 Rubin Institute for Advanced Orthopedics, Sinai Hospital, 2401 West Belvedere Avenue, Baltimore, MD 21215. E-mail address: jconway@lifebridgehealth.org

The first 150 words of the full text of this article appear below.


   Introduction
 
Treatment of infected nonunions is a challenge faced by many orthopaedic surgeons. Traditionally, the treatment strategy has been control of the infection followed by procedures to achieve osseous union. Débridement, antibiotic-impregnated cement beads, and intravenous antibiotics have been used for the control of the infection1-3. External or internal fixation methods have been used to achieve stability to promote union. Antibiotic cement-coated intramedullary nails can be used to treat the infection with high doses of local antibiotics and to provide bone stability4. Use of these devices allows immediate weight-bearing and prevents many complications associated with external fixation, such as pin-track infections and joint stiffness. This novel approach to the treatment of infected nonunions was developed to minimize the number of additional surgical procedures required for infection control and to achieve bone union. We present our series of fifty-two patients in whom an antibiotic cement-coated intramedullary nail was inserted for . . . [Full Text of this Article]


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