The Journal of Bone and Joint Surgery (American). 2008;90:438-442.
doi:10.2106/JBJS.G.01092
© 2008 The Journal of Bone and Joint Surgery, Inc.
An AAOS-NIH SymposiumFracture Repair: Challenges, Opportunities, and Directions for Future Research*
Thomas A. Einhorn, MD1,
Cato T. Laurencin, MD, PhD2 and
Karen Lyons, PhD3
1 Department of Orthopaedic Surgery, Boston University Medical Center, 720 Harrison Avenue, Suite 808, Boston, MA 02118. E-mail address: thomas.einhorn@bmc.org
2 Department of Orthopaedic Surgery, University of Virginia, 400 Ray C. Hunt Drive, Suite 300, Charlottesville, VA 22936. E-mail address: laurencin@virgnia.edu
3 Department of Orthopaedic Surgery, University of California, Los Angeles, 615 Charles E. Young Drive South, 410C OHRC, Los Angeles, CA 90095. E-mail address: klyons@mednet.ucla.edu
| The first 150 words of the full text of this article appear below. |
 |
Introduction
|
|---|
Fracture-healing is a complex, highly organized biological process that leads to the restoration of skeletal integrity by the regeneration of bone. This unique property differentiates bone from other tissues and is essential for skeletal health, homeostasis, and survival. Although fracture-healing is one of the most consistent and reliable reparative responses of human tissue, its impairment or failure can lead to devastating clinical consequences. Conversely, a comprehensive understanding of the basic science of fracture-healing may reveal some of the most well-kept secrets of nature, providing clinicians and scientists with new paths for investigation and leading to advanced therapies for the treatment of skeletal injuries and diseases. This article summarizes the key discussion points of the 2007 American Academy of Orthopaedic Surgeons (AAOS) Research Symposium entitled "Fracture Repair: Challenges and Opportunities." The major goals of this meeting were (1) to identify the unmet needs and research directions for basic, translational, and clinical . . . [Full Text of this Article]

CiteULike Connotea Del.icio.us Technorati What's this?
|