The Journal of Bone and Joint Surgery (American). 2007;89:21-33.
doi:10.2106/JBJS.F.00754
© 2007 The Journal of Bone and Joint Surgery, Inc.
Natural History of Early Onset Scoliosis
Pedro Fernandes, MD and
Stuart L. Weinstein, MD
Corresponding author: Stuart L. Weinstein, MD Division of Pediatric
Orthopaedics and Spine Deformity, Department of Orthopaedic Surgery,
University of Iowa Hospitals and Clinics, 01026 JPP, 200 Hawkins Drive, Iowa
City, IA 52242. E-mail address:
stuart-weinstein@uiowa.edu
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Introduction
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Idiopathic scoliosis is a structural, lateral curvature of the spine of
unknown etiology that can occur in otherwise normal children and adolescents.
It is a condition that is affected by growth during the first two decades of
life. Harrenstein, in
19361, coined the
term infantile idiopathic scoliosis. He related it to rickets, stating that
the curve responded well to bracing. In 1951,
James2, in his
preliminary report on infantile idiopathic scoliosis, described the cases of
thirty-three infants who were three years of age or less and had a structural
left thoracic curve with no apparent etiology. Most of the infants were boys.
The scoliosis in these infants occasionally resolved, but when it did progress
it tended to progress to a very serious deformity. Later, in 1954, he
classified idiopathic scoliosis into three groups on the basis of age of
onset: infantile scoliosis with onset up to three years . . . [Full Text of this Article]

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