The Journal of Bone and Joint Surgery (American). 2007;89:1605-1618.
doi:10.2106/JBJS.F.00901
© 2007 The Journal of Bone and Joint Surgery, Inc.
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Current Concepts Review

Prevention of Perioperative Infection

Nicholas Fletcher, MD1, D'Mitri Sofianos, BS1, Marschall Brantling Berkes, BS1 and William T. Obremskey, MD, MPH1

1 Vanderbilt Orthopedic Trauma, Medical Center East–South Tower, Suite 4200, Nashville, TN 37232-8774. E-mail address for W.T. Obremskey: william.obremskey@vanderbilt.edu

Investigation performed at Vanderbilt Orthopedic Trauma, Nashville, Tennessee

The first 150 words of the full text of this article appear below.


   Introduction
 

  • Formula Administration of preoperative antibiotics is associated with reduced rates of surgical site infections.
  • Formula Antibiotics should be continued for no longer than twenty-four hours after elective surgery or surgical treatment of closed fractures.
  • Formula Chlorhexidine gluconate is superior to povidone-iodine for preoperative antisepsis for the patient and surgeon.
  • Formula Closed suction drainage is not warranted in elective total joint replacement. It is associated with an increased relative risk of transfusions. Drains left in situ for more than twenty-four hours are at an increased risk for bacterial contamination.
  • Formula The rate of postoperative infections associated with occlusive dressings is lower than that associated with nonocclusive dressings.
  • Formula Appropriate management of blood glucose levels, oxygenation, and the temperature of the patient reduces the risk of postoperative infection.

Surgical site infection is one of the most common complications that a surgeon encounters, with an infection occurring after approximately 780,000 operations in the United States each . . . [Full Text of this Article]


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