The Journal of Bone and Joint Surgery (American). 2007;89:910-913.
doi:10.2106/JBJS.F.00998
© 2007 The Journal of Bone and Joint Surgery, Inc.
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The Legal and Ethical Issues Surrounding Financial Conflict of Interest in Orthopaedic Research

Kanu Okike, BA1 and Mininder S. Kocher, MD, MPH2

1 Department of Orthopaedic Surgery, Children's Hospital, Harvard Medical School, 300 Longwood Avenue, Boston, MA 02115. E-mail address: kanu_okike@hms.harvard.edu
2 Department of Orthopaedic Surgery, Children's Hospital Boston, 300 Longwood Avenue, Boston, MA 02115

The first 150 words of the full text of this article appear below.


   Introduction
 
CASE 1. An orthopaedic surgeon publishes a paper featuring a positive evaluation of a new medication to prevent deep venous thrombosis. The surgeon serves as a paid consultant to the drug manufacturer.

CASE 2. An orthopaedic surgeon is asked by a medical device company to conduct a study evaluating a novel total hip prosthesis. The device manufacturer assumes responsibility for funding the study and publishing the results.

CASE 3. An orthopaedic surgeon has developed a novel synthetic tendon graft, which she hopes to market after obtaining approval from the United States Food and Drug Administration (FDA). She seeks to enroll one of her patients in a clinical trial of the graft.

Conflict of interest has been defined as "a set of conditions in which professional judgment concerning a primary interest (such as a patient's welfare or the validity of research) tends to be unduly influenced by a . . . [Full Text of this Article]


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