The Journal of Bone and Joint Surgery (American). 2006;88:138-147.
doi:10.2106/JBJS.F.00609
© 2006 The Journal of Bone and Joint Surgery, Inc.
Periprosthetic Infection: What Are the Diagnostic Challenges?
Javad Parvizi, MD, FRCS,
Elie Ghanem, MD,
Sarah Menashe, BS,
Robert L. Barrack, MD and
Thomas W. Bauer, MD, PhD
Corresponding author: Javad Parvizi, MD, FRCS 925 Chestnut Street,
Philadelphia, PA 19107. E-mail
address: parvj@aol.com
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Introduction
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Periprosthetic infection remains one of the most challenging complications
of total joint arthroplasty. Despite the substantial reduction in the
prevalence of this complication over the last two decades, periprosthetic
infection is the second most common complication of joint arthroplasty, after
loosening1,2.
Infection has been reported to occur in association with 1% to 4% of primary
total knee
arthroplasties3,4
and about 1% of primary total hip
arthroplasties5,6.
The prevalence of periprosthetic infection after revision arthroplasty is much
higher, reported to be 3.2% for hips and 5.6% for
knees7. It is
believed that the prevalence of periprosthetic infection is on the rise once
again8. The
treatment of periprosthetic infection differs vastly from the treatment of
aseptic loosening. Hence, it is paramount to distinguish between septic and
aseptic joint failures preoperatively.
The diagnosis of infection after total joint arthroplasty continues to pose
a challenge, particularly when it presents as . . . [Full Text of this Article]

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