The Journal of Bone and Joint Surgery (American). 2006;88:11-19.
doi:10.2106/JBJS.F.00635
© 2006 The Journal of Bone and Joint Surgery, Inc.
Management of Lower-Extremity Bone Metastasis
Kristy L. Weber, MD,
R. Lor Randall, MD,
Seth Grossman, MS and
Javad Parvizi, MD
Corresponding author: Kristy L. Weber, MD Department of Orthopaedic
Surgery, Johns Hopkins School of Medicine, 601 North Caroline Street, JHOC
#5251, Baltimore, MD 21287. E-mail address:
Kweber6@jhmi.edu
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Introduction
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The incidence of metastatic bone disease is increasing as patients with
cancer are living
longer1. Although
malignant skeletal tumors are usually initially managed by orthopaedic
surgeons with expertise in oncology, patients with metastatic disease of the
bone may seek medical care at community hospitals. Hence, general orthopaedic
surgeons may often be required to care for patients with metastatic bone
disease. The overall care of such patients often requires a multidisciplinary
team of health-care providers, including a medical oncologist, radiation
oncologist, orthopaedic surgeon, pathologist, radiologist, physical therapist,
and chaplain1. There
are multiple factors to consider in the treatment of patients with bone
metastasis, including comorbidities, the histological characteristics of the
primary tumor, the expected life span of the patient, the patient's activity
level, and pain.
Surgical considerations involve the same issues in addition to the location
of the tumor and the presence of neurologic symptoms. Occasionally,
nonoperative treatment is . . . [Full Text of this Article]

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