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The Journal of Bone and Joint Surgery (American) 85:3-7 (2003)
© 2003 The Journal of Bone and Joint Surgery, Inc.

Marshall R. Urist Lectures

Marshall R. Urist: A Renaissance Scientist and Orthopaedic Surgeon

A. Hari Reddi, PhD

Corresponding author: A. Hari Reddi, PhD
Center for Tissue Regeneration and Repair, Department of Orthopaedic Surgery, School of Medicine, University of California, Davis, 4635 Second Avenue, Research Building I, Room 2000, Sacramento, CA 95817. E-mail address: ahreddi@ucdavis.edu

The author did not receive grants or outside funding in support of the research or preparation of this manuscript. He did not receive payments or other benefits or a commitment or agreement to provide such benefits from a commercial entity. No commercial entity paid or directed, or agreed to pay or direct, any benefits to any research fund, foundation, educational institution, or other charitable or nonprofit organization with which the author is affiliated or associated.

The first 150 words of the full text of this article appear below.

In 1965, Marshall R. Urist discovered that the intramuscular implantation of demineralized bone matrix elicits new bone formation. This discovery, made in the Bone Research Laboratory of the University of California, Los Angeles (UCLA), marked the beginning of the development of knowledge concerning bone morphogenetic proteins (BMPs). Stimulated by Urist's observations, research on BMPs was undertaken in laboratories throughout the world, and, in the last decade, the advance of knowledge pertaining to the capacity of BMPs to induce the healing of segmental bone defects has been phenomenal. This article briefly describes Marshall Urist's career as a scientist and orthopaedic surgeon, his life, his family, and his friends.

Marshall R. Urist was born on June 11, 1914. He was raised in South Haven, Michigan. He attended the Crane Technical High School and had an abiding interest in architecture. He continued his studies at the University of Michigan, where he came under . . . [Full Text of this Article]


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