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The Journal of Bone and Joint Surgery (American) 85:70-77 (2003)
© 2003 The Journal of Bone and Joint Surgery, Inc.

Scientific Article

New MRI Techniques for Imaging Cartilage

Deborah Burstein, PhD and Martha Gray, PhD

Corresponding author: Deborah Burstein, PhD
Department of Radiology, Beth Israel Deaconess Medical Center, 4 Blackfan Circle, Room 148, Boston, MA 02115. E-mail address: dburstei@caregroup.harvard.edu

In support of their research or preparation of this manuscript, one or more of the authors received grants or outside funding from the National Institutes of Health (grants AR42773 and RR14792), the Arthritis Foundation (Clinical Science Grant), and the Edwin Hood Taplin Professorship. One of the authors has received a grant from Genzyme Corporation for clinical research studies. None of the authors received payments or other benefits or a commitment or agreement to provide such benefits from a commercial entity. No commercial entity paid or directed, or agreed to pay or direct, any benefits to any research fund, foundation, educational institution, or other charitable or nonprofit organization with which the authors are affiliated or associated.

The first 150 words of the full text of this article appear below.


   Introduction
 
Because of its ability to image all of the tissues in a diarthrodial joint, magnetic resonance imaging (MRI) has an ever-increasing role in the evaluation, diagnosis, and monitoring of joint disorders. Standard MRI techniques can delineate morphologic abnormalities. Techniques on the horizon offer improved morphologic analysis as well as previously unavailable information about the biochemical composition and functional properties of joint tissues. While research and development efforts are rapidly growing, the current review focuses on techniques that are most advanced and that have demonstrated feasibility in basic science and clinical studies. As such, we report mainly on cartilage imaging but hasten to add that ongoing research efforts offer promise for the imaging of all joint structures. These techniques should improve our ability to understand the healthy joint and the disease process, to provide earlier diagnoses, and to evaluate the effects of therapeutic procedures. With these capabilities, we can more effectively . . . [Full Text of this Article]


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