The Journal of Bone and Joint Surgery (American) 84:1856-1860 (2002)
© 2002 The Journal of Bone and Joint Surgery, Inc.
Invasive Pigmented Villonodular Synovitis of the Atlantoaxial Joint
A Case Report
Eric J. Graham, MD,
Timothy R. Kuklo, MD,
Michael Kyriakos, MD,
David A. Rubin, MD and
K. Daniel Riew, MD
Investigation performed at the Department of Orthopaedic Surgery, Washington University School of Medicine, St. Louis, Missouri
Eric J. Graham, MD
Timothy R. Kuklo, MD
Michael Kyriakos, MD
David A. Rubin, MD
K. Daniel Riew, MD
Departments of Orthopaedic Surgery (E.J.G, T.R.K, and K.D.R.), Pathology (M.K.), and Radiology (D.A.R.), Barnes-Jewish Hospital at Washington University, St. Louis, MO. E-mail address for K.D. Riew: riewd@msnotes.wustl.edu
The authors did not receive grants or outside funding in support of their research or preparation of this manuscript. They did not receive payments or other benefits or a commitment or agreement to provide such benefits from a commercial entity. No commercial entity paid or directed, or agreed to pay or direct, any benefits to any research fund, foundation, educational institution, or other charitable or nonprofit organization with which the authors are affiliated or associated.
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Introduction
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Pigmented villonodular synovitis is a slowly progressive lesion that originates from the synovial membrane of the tendons and joints 1-6 . It most frequently occurs in the hip and knee joints as a monoarticular proliferative process but may arise in any joint 1,2,7,8 . However, the cervical spine is an uncommon site of involvement, with the cases of only twelve patients previously reported in the English-language literature, to our knowledge 9-15 . The lesion was in proximity to the first and second cervical levels in only one of these patients 15 ; the lesions in the remaining patients involved the subaxial cervical spine. We describe a patient who had a unique case of pigmented villonodular synovitis involving not only the facet joint at the first and second cervical level but also the first and second cervical vertebrae.
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Case Report
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A forty-six-year-old woman was seen because of a nine-month history of neck pain. She reported that she . . . [Full Text of this Article]

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