The Journal of Bone and Joint Surgery (American) 84:106-111 (2002)
© 2002 The Journal of Bone and Joint Surgery, Inc.
Malignant Fibrous Histiocytoma at the Site of a Previously Treated Aneurysmal Bone Cyst
A Case Report
P. Anract, MD,
G. dePinieux, MD,
C. Jeanrot, MD,
A. Babinet, MD,
M. Forest, MD and
B. Tomeno, MD
Investigation performed at the Cochin Teaching Hospital, University
Paris V, Paris, France
P. Anract, MD
G. de Pinieux, MD
C. Jeanrot, MD
A. Babinet, MD
M. Forest, MD
B. Tomeno, MD
Departments of Oncologic Orthopedic Surgery (P.A., C.J., A.B.,
and B.T.) and Pathology (G. de P. and M.F.), Cochin Teaching Hospital,
University Paris V, 27 rue du Faubourg Saint Jacques, 75679 Paris
Cedex 14, France. E-mail address for P. Anract: philippe.anract@cch.ap-hop-paris.fr
No benefits in any form have been received or will be received from
a commercial party related directly or indirectly to the subject
of this article. No funds were received in support of this study.
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Introduction
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Jaffe and Lichtenstein1 described
aneurysmal bone cyst as a benign non-neoplastic lesion of unknown
etiology. Aneurysmal bone cysts can be primary or secondary to other
bone tumors, including nonossifying fibroma, chondroblastoma, giant-cell
tumor of bone, osteoblastoma, fibrous dysplasia, fibromyxoma, osteoblastoma,
solitary bone cyst, hemangioendothelioma, osteosarcoma, and metastatic
carcinoma2,3.
Although several cases of malignant transformation have been reported,
most were either radiation-induced sarcomas or telangiectatic osteosarcomas
that had been misdiagnosed as aneurysmal bone cyst. To our knowledge,
the literature contains only one report of satisfactorily documented
malignant transformation of an aneurysmal bone cyst4.
We describe a patient who had a malignant fibrous histiocytoma
at the site of a femoral aneurysmal bone cyst that had been treated
twelve years earlier by curettage and internal fixation after a
pathological fracture.
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Case Report
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A twenty-eight-year-old man was admitted to our institution in
December 1986 because of a pathological supracondylar fracture of
the left femur. . . . [Full Text of this Article]

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