The Journal of Bone and Joint Surgery (American) 84:101-105 (2002)
© 2002 The Journal of Bone and Joint Surgery, Inc.
Reactivation of Ancient Tuberculous Arthritis of the Hip Following Total Hip Arthroplasty
A Case Report
Ronald Hugate, Jr., MD and
Vincent D. Pellegrini, Jr., MD
Investigation performed at The Milton S. Hershey Medical Center,
The Pennsylvania State University College of Medicine, Hershey,
Pennsylvania
Ronald Hugate Jr., MD
Vincent D. Pellegrini Jr., MD
Department of Orthopaedics and Rehabilitation, The Milton S.
Hershey Medical Center, The Pennsylvania State University College
of Medicine, 500 University Drive, Hershey, PA 17033. E-mail address
for V.D. Pellegrini Jr.: vpellegrini@psu.edu
No benefits in any form have been received or will be received from
a commercial party related directly or indirectly to the subject
of this article. No funds were received in support of this study.
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Introduction
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The literature on the treatment of ancient tuberculous arthritis with
late total joint replacement is sparse, and there is no clearly
recommended plan of care. We report the case of a patient who had
reactivation of Mycobacterium tuberculosis following
total hip arthroplasty after sixty-four years of quiescence. Several
key points regarding clinical strategies are explored, including
assessment of the need for chemoprophylaxis, the importance of long
periods of quiescence of active tuberculosis, and the options for
treating tuberculous infection at the site of a joint replacement.
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Case Report
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The patient was a seventy-one-year-old man with a history of isolated
tuberculous arthritis of the left hip at the age of three years.
Initially, he had been treated with a hip-spica cast, followed by
an arthrodesis in 1932 at the age of five years. He received no
chemotherapy at that time as antituberculous drugs were not available.
The hip remained functional and pain-free for . . . [Full Text of this Article]

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