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The Journal of Bone and Joint Surgery 83:355 (2001)
© 2001 The Journal of Bone and Joint Surgery, Inc.

The Use of Calcium Sulfate in the Treatment of Benign Bone Lesions

A Preliminary Report

Raffy Mirzayan, MD, Vahé Panossian, MD, Raffi Avedian, BS, Deborah M. Forrester, MD and Lawrence R. Menendez, MD

Investigation performed at the University Hospital, Department of Orthopaedic Surgery, Keck School of Medicine, University of Southern California, Los Angeles, California


   Introduction
 
Bone grafts are widely used by surgeons to correct bone defects resulting from a variety of causes, including tumors, trauma, and infection. Autogenous bone remains the ideal material for grafting because it is not antigenic and it has both osteoinductive and osteogenic properties1. The harvesting of autogenous bone, however, can be associated with substantial complications. The common problems that have been reported include pain at the donor site, palsy of the lateral femoral cutaneous nerve, injury of the superior gluteal artery, pelvic fracture, hematoma, infection, and gait disturbances2. Furthermore, the amount of autogenous bone graft available for harvesting is limited and may be insufficient to fill large osseous defects. The quality of the harvested autogenous bone is also variable1. Because of the complications associated with harvesting autogenous bone and its limited supply, many surgeons have sought bone-graft-substitute materials.

A bone-graft substitute that has regained popularity recently is . . . [Full Text of this Article]


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