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The Journal of Bone and Joint Surgery (American) 83:S161-161 (2001)
© 2001 The Journal of Bone and Joint Surgery, Inc.


Commentary

Clinical Application of the BMPs

Scott D. Boden, MD, Director

The Emory Spine Center, Emory University School of Medicine, 2165 N. Decatur Road, Decatur, GA 30033

The author did not receive grants or outside funding in support of his research or preparation of this manuscript. The author received payments or other benefits or a commitment or agreement to provide such benefits from commercial entities (Medtronics Sofamor-Danek, Sulzer Biologies, Osteotech, Wright Medical). No commercial entity paid or directed, or agreed to pay or direct, any benefits to any research fund, foundation, educational institution, or other charitable or nonprofit organization with which the author is affiliated or associated.

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It has been almost 40 years since Marshall Urist’s seminal observations on the bone induction principle were first published, yet we have not seen the common use of bone morphogenetic proteins (BMPs) in our patients. I believe that two obstacles have delayed this translation: (1) underestimation of the need for a higher concentration or dose of BMPS . . . [Full Text of this Article]


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