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The Journal of Bone and Joint Surgery 82:1323 (2000)
© 2000 The Journal of Bone and Joint Surgery, Inc.

Evidence-Based Orthopaedics

Commentary

Hans J. Kreder, M.D., M.P.H. F.R.C.S.(C)

Sunnybrook & Women's College Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada

Nonsteroidal anti-inflammatory medication is effective treatment for the symptoms associated with osteoarthritis. However, potentially serious toxic effects limit its use in some individuals. Glucosamine and chondroitin represent normal components of articular cartilage that have been under investigation as potential disease-modifying and symptom-ameliorating agents.

McAlindon and colleagues have investigated the potential benefits of . . . [Full Text of this Article]


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