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The Journal of Bone and Joint Surgery 82:1323 (2000)
© 2000 The Journal of Bone and Joint Surgery, Inc.

Evidence-Based Orthopaedics

Glucosamine and chondroitin were found to improve outcomes in patients with osteoarthritis

T E McAlindon, M P LaValley, J P Gulin and D T Felson

Source of funding: National Institutes of Health.
For correspondence: Dr. T.E. McAlindon, The Arthritis Center, Boston University School of Medicine, 715 Albany St., A203, Boston, MA 02118, USA. FAX: 617-638-5239.

McAlindon TE, LaValley MP, Gulin JP, Felson DT. Glucosamine and chondroitin for treatment of osteoarthritis: a systematic quality assessment and meta- analysis. JAMA. 2000 Mar 15;283: 1469-75.

Question: In patients with osteoarthritis, are glucosamine and chondroitin effective for relieving symptoms and improving function?

Data sources: Studies were identified by searching MEDLINE (1966 to June 1999) and the Cochrane Controlled Trials Register. Bibliographies of articles and meeting abstracts published in supplements of Arthritis and Rheumatism, the British Journal of Rheumatology, and Osteoarthritis and Cartilage . . . [Full Text of this Article]


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