The Journal of Bone and Joint Surgery 82:1197 (2000)
© 2000 The Journal of Bone and Joint Surgery, Inc.
Pinealectomy and Scoliosis
Tamás Illés, M.D., Ph.D.,
Gyözö Horvath, M.D.,
Keith M. Bagnall, Ph.D.,
V. James Raso, M.Sc.,
Marc Moreau, M.D.,
James Mahood, M.D.,
Xiaoping Wang, M.D. and
Jie Zhao, M.D.
Corresponding author: Tamás Illés, M.D., Ph.D.
Department of Orthopaedic Surgery
University Medical School of Pécs
Ifjúság Street 13
Pécs H-7643, Hungary
Corresponding author: Keith M. Bagnall, Ph.D.
Division of Anatomy and Department of Surgery
University of Alberta
Edmonton, Alberta T6G 2H7, Canada
E-mail address: kbagnall@med.ualberta.ca
To The Editor:
The article "The Effects of Melatonin Therapy on the Development
of Scoliosis After Pinealectomy in the Chicken" (81-A: 191-199,
Feb. 1999), by Bagnall et al., is a very well designed study of
the "pinealectomized chicken" model that had the intention of addressing
almost all of the main controversial issues in this field. First of
all, we congratulate the authors for their work, which we consider
to be one of the most comprehensive studies to date, but we wish
to make remarks concerning two aspects.
Our first comment concerns the ratio of scoliosis. On the basis
of our experience of operating on more than 200 broiler chickens,
we can report that the scoliosis induced by pinealectomy is in inverse
relation to the number of days between hatching and pinealectomy.
When we carried out pinealectomy on the first day after hatching, we
found scoliosis in more than 80 percent . . . [Full Text of this Article]

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