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The Journal of Bone and Joint Surgery 82:873 (2000)
© 2000 The Journal of Bone and Joint Surgery, Inc.

Evidence-Based Orthopaedics

Vitamin C reduced the incidence of reflex sympathetic dystrophy after wrist fracture

P E Zollinger, W E Tuinebreijer, R W Kreis and R S Breederveld

Source of funding: Not stated.
For correspondence: Dr. P.E. Zollinger, Buizerdstraat 50, 2665 TG, Bleiswijk, The Netherlands.

Zollinger PE, Tuinebreijer WE, Kreis RW, Breederveld RS. Effect of vitamin C on frequency of reflex sympathetic dystrophy in wrist fractures: a randomised trial. Lancet. 1999 Dec 11;354:2025-8.

Question: In patients with wrist fractures, does vitamin C reduce the incidence of posttraumatic reflex sympathetic dystrophy (RSD)?

Design: Randomized (allocation concealed), double-blind, placebo-controlled trial with 1-year . . . [Full Text of this Article]


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