The Journal of Bone and Joint Surgery 82:281-87 (2000)
© 2000 The Journal of Bone and Joint Surgery, Inc.
Commentary - Design Issues in Clinical Studies of the in Vivo Volumetric Wear Rate of Polyethylene Bearing Components*
GLADIUS LEWIS, Ph.D.
The issue of wear of ultra-high molecular weight polyethylene bearing surfaces in total hip and knee replacements is, without doubt, one of the dominant themes in contemporary orthopaedics. Thus, an array of relevant facets of this topic have been extensively and intensively researched, spawning, in the process, a very large volume of literature.
The main topics that have been studied are the place of wear in the hierarchy of degradation modes of polyethylene bearing surfaces, the role of polyethylene wear particles in the in vivo longevity of the prosthesis, the methods of determining the extent of wear of polyethylene bearing components (for example, the acetabular cup, acetabular cup liner, or tibial insert), the magnitude of the volumetric wear rate, the relationship between the results of in vitro wear-testing of polyethylene specimens or components and the clinical performance of polyethylene components, and the key factors influencing the clinical wear of polyethylene . . . [Full Text of this Article]

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