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The Journal of Bone and Joint Surgery 82:1634 (2000)
© 2000 The Journal of Bone and Joint Surgery, Inc.

Metastasis of Osteosarcoma to Soft Tissue

A Case Report*

Timothy A. Damron, M.D.{dagger}, Chris Morganti, M.D.{dagger}, Yi Yang, M.D., Ph.D.{dagger}, Leonard Hojnowski, M.D.{dagger} and Richard Cherny, M.D.{ddagger}

Investigation performed at the Departments of Orthopedics, Pathology, and Radiology, State University of New York Upstate Medical University, Syracuse
*No benefits in any form have been received or will be received from a commercial party related directly or indirectly to the subject of this article. No funds were received in support of this study.
{dagger}Departments of Orthopedics (T. A. D. and C. M.), Pathology (Y. Y.), and Radiology (L. H.), State University of New York Upstate Medical University at Syracuse, 550 Harrison Street, Suite 100, Syracuse, New York 13202. E-mail address for T. A. Damron: damront@upstate.edu.
{ddagger}Central New York Oncology Associates, 1000 East Genesee, Syracuse, New York 13210.


   Introduction
 
Metastases to soft tissue from any source are rare, with carcinomas being the most common primary lesion8,9. Metastases from osteosarcomas most commonly are observed in the lungs or bone and rarely are observed elsewhere in the absence of widely disseminated disease10. We present the case of a patient with a distal femoral osteosarcoma who, at the time of diagnosis, had an isolated metastasis to the soft tissue of the chest wall. The purpose of this report is to emphasize the need to consider metastatic disease as a possible explanation for any soft-tissue mass that is discovered at the time of diagnosis, or during treatment, of osteosarcoma.


   Case Report
 
A thirty-six-year-old man came to us with a two-month history of pain and swelling in the right knee. The patient had been taking ibuprofen to relieve the pain, which initially had been a mild, constant ache involving both the knee and the . . . [Full Text of this Article]


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