The Journal of Bone and Joint Surgery (American) 82:114-26 (2000)
© 2000 The Journal of Bone and Joint Surgery, Inc.
Instructional Course Lecture |
Instructional Course Lectures, The American Academy of Orthopaedic Surgeons - Operative Treatment for Metastatic Disease of the Pelvis and the Proximal End of the Femur*
TIMOTHY A. DAMRON, M.D. , SYRACUSE, NEW YORK and
FRANKLIN H. SIM, M.D. , ROCHESTER, MINNESOTA
An Instructional Course Lecture, American Academy of Orthopaedic Surgeons
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Introduction
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The prognosis for patients who have invasive cancer continues to improve. According to the statistics of the American Cancer Society3 for 1988 through 1992, the five-year survival rate for patients who have prostate cancer is 90 percent for whites and 75 percent for blacks and the five-year survival rate for patients who have breast cancer is 86 percent for whites and 70 percent for blacks. However, estimates suggest that 50 percent of the 1,228,600 new cases of invasive cancer diagnosed each year will eventually metastasize to bone3.
Many of these metastatic lesions involve the pelvis and the proximal end of the femur. In fact, the pelvis is second only to the spine in terms of the frequency of osseous involvement by metastatic disease, and the proximal end of the femur is the most common site of long-bone involvement by metastatic disease. While the recent introduction of bisphosphonates, which counteract . . . [Full Text of this Article]

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