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The Journal of Bone and Joint Surgery 81:1170-2 (1999)
© 1999 The Journal of Bone and Joint Surgery, Inc.

Hemolytic Disease of the Newborn Caused by Transfusion of a Husband's Directed Blood Donation. A CASE REPORT*

MELANIE S. KENNEDY, M.D.{dagger}, RICHARD O'SHAUGHNESSY, M.D.{ddagger}, RAY C. WASIELEWSKI, M.D.§, ABDUL WAHEED, M.S., M.T.#, MARTHA HEWITT, M.T.# and DAVID KRUGH, M.T.#, COLUMBUS, OHIO

Investigation performed at the Departments of Pathology, Obstetrics and Gynecology, and Surgery, College of Medicine, Ohio State University, Columbus


   Introduction
 
The demand for directed blood donation in the United States is small but consistent20,21. However, with our current knowledge of alloimmunization and graft-versus-host disease, directed blood donation has been shown to have adverse effects in some recipients1,10,19. To prevent graft-versus-host disease, the Standards Committee of the American Association of Blood Banks1 now requires gamma irradiation of blood that has been donated by the blood relatives of patients. Furthermore, the latest edition of the Technical Manual of the American Association of Blood Banks advises that a woman who is planning to bear children should not receive a transfusion of red blood cells from her sexual partner or his blood relatives19.

We report a case of hemolytic disease of the newborn that was caused by the transfusion of red blood cells from a husband to his wife after she had an elective total hip replacement five months before becoming . . . [Full Text of this Article]


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