The Journal of Bone and Joint Surgery 81:409-13 (1999)
© 1999 The Journal of Bone and Joint Surgery, Inc.
Multifocal, Metachronous Giant-Cell Tumor of the Ulna. A Case Report*
YONG-KOO PARK, M.D. ,
KYUNG NAM RYU, M.D. ,
CHUNG-SOO HAN, M.D. and
DAE KYUNG BAE, M.D. , SEOUL, KOREA
Investigation performed at the Departments of Pathology, Diagnostic Radiology, and Orthopedic Surgery, College of Medicine, Kyung Hee University, Seoul
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Introduction
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Giant-cell tumor of bone apparently was first described by Cooper and Travers5 in 1818. In 1996, the condition was reported to account for approximately 5 percent of all primary bone tumors in a series from the Mayo Clinic34. Multicentric giant-cell tumor of bone has been reported in the literature3,7-9,11,14,15,19,21,24,26-28,32,35. The term multicentric usually refers to the occurrence of a primary bone tumor in two bones or more at approximately the same timethat is, synchronous involvement of two bones or more by the same type of tumor. However, in some of the patients described in previous reports, multifocal involvement of the skeleton occurred over a period of years. We report a rare case of multifocal involvement in which a second giant-cell tumor occurred in the diaphysis of the ulna ten years after the resection of a giant-cell tumor from the distal part of that bone. Because of disagreement about . . . [Full Text of this Article]

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