This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Letters to the Editor: Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when Letters to the Editor are posted
Right arrow Alert me if a correction is posted
Services
Right arrow E-mail this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My File Cabinet
Right arrow Download to citation manager
Right arrowReprints and Permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by REMPEL, D.
Right arrow Articles by LUNDBORG, G.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by REMPEL, D.
Right arrow Articles by LUNDBORG, G.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us   Add to Technorati  
What's this?
The Journal of Bone and Joint Surgery 81:1600-10 (1999)
© 1999 The Journal of Bone and Joint Surgery, Inc.

Current Concepts Review

Pathophysiology of Nerve Compression Syndromes: Response of Peripheral Nerves to Loading*

DAVID REMPEL, M.D., M.P.H.{dagger}, SAN FRANCISCO, CALIFORNIA, LARS DAHLIN, M.D., PH.D.{ddagger} and GÖRAN LUNDBORG, M.D., PH.D.{ddagger}, MALMÖ, SWEDEN


   Introduction
 
Nerve compression syndromes involve peripheral-nerve dysfunction that is due to localized interference of microvascular function and structural changes in the nerve or adjacent tissues. Although a well known example is compression of the median nerve at the wrist (carpal tunnel syndrome), other nerves, such as the ulnar nerve at the wrist or the elbow and the spinal nerve roots at the vertebral foramen, are vulnerable. This paper focuses on studies in which the physiological, pathophysiological, biochemical, and histological effects of biomechanical loading on the peripheral nerves were evaluated in humans and animals.

When tissues are subjected to load or pressure, they deform and pressure gradients are formed, redistributing the compressed tissue toward areas of lower pressure. Nerve compression syndromes usually occur at sites where the nerve passes through a tight tunnel formed by stiff tissue boundaries. The resultant confined space limits movement of tissue and can lead to sustained tissue . . . [Full Text of this Article]


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us   Add to Technorati Technorati    What's this?


This article has been cited by other articles:


Home page
 J Ultrasound MedHome page
I. H. Lee, Y. C. Yoon, E. Y. Cho, J. W. Kwon, and S. T. Kwon
Perineural Air Injection as a Means of Prevention of Thermal Injury of the Sciatic Nerve During Radio Frequency Ablation: A Preliminary Experimental Study in Rabbits
J. Ultrasound Med., August 1, 2008; 27(8): 1221 - 1227.
[Abstract] [Full Text] [PDF]

Home page
 J Am Acad Orthop SurgHome page
B. Elhassan and S. P. Steinmann
Entrapment Neuropathy of the Ulnar Nerve
J. Am. Acad. Ortho. Surg., November 1, 2007; 15(11): 672 - 681.
[Abstract] [Full Text] [PDF]

Home page
 NeurologyHome page
R. Beekman, J. H.J. Wokke, M. C. Schoemaker, M. L. Lee, and L. H. Visser
Ulnar neuropathy at the elbow: Follow-up and prognostic factors determining outcome
Neurology, November 9, 2004; 63(9): 1675 - 1680.
[Abstract] [Full Text] [PDF]

Home page
 NeurologyHome page
R. Beekman, M. C. Schoemaker, J. P.L. van der Plas, L. H. van den Berg, H. Franssen, J. H.J. Wokke, B. M.J. Uitdehaag, and L. H. Visser
Diagnostic value of high-resolution sonography in ulnar neuropathy at the elbow
Neurology, March 9, 2004; 62(5): 767 - 773.
[Abstract] [Full Text] [PDF]

Home page
 Clin. Chem.Home page
M. A.J. van Dijk, J. B. Reitsma, J. C. Fischer, and G. T.B. Sanders
Indications for Requesting Laboratory Tests for Concurrent Diseases in Patients with Carpal Tunnel Syndrome: A Systematic Review
Clin. Chem., September 1, 2003; 49(9): 1437 - 1444.
[Abstract] [Full Text] [PDF]

Home page
 NEJMHome page
J. N. Katz and B. P. Simmons
Carpal Tunnel Syndrome
N. Engl. J. Med., June 6, 2002; 346(23): 1807 - 1812.
[Full Text] [PDF]