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The Journal of Bone and Joint Surgery 80:1395 (1998)
© 1998 The Journal of Bone and Joint Surgery, Inc.

Correspondence

Correspondence

Marwan A. Wehbé, M.D. and Charles R. Clark, M.D.

TO THE EDITOR:

Prospective, randomized, double-blind studies can be false, erroneous, and misleading!

In "Editorial. The Prospective, Randomized, Double-Blind Clinical Trial in Orthopaedic Surgery" (79-A: 1191-1120, Aug. 1997), Clark eloquently discussed the virtues of such studies, leaving the reader with the impression that the ultimate study must have that format. Indeed, our medical students and residents have been convinced that these are the only studies of value.

In particular clinical settings, this approach can lead to the wrong conclusion, bias health-care decisions, and, ultimately, stifle progress. Consider, for instance, a study that purports to examine the effect of tenosynovectomy or neurolysis in patients managed with carpal tunnel release. . . . [Full Text of this Article]


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