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The Journal of Bone and Joint Surgery 80:1394-1395 (1998)
© 1998 The Journal of Bone and Joint Surgery, Inc.

Correspondence

Correspondence

Mark T. Drangsholt, D.D.S., M.P.H., John M. Deacon, M.D., Andre J. Pagliaro, M.D., Steven B. Zelicof, M.D., Ph.D. and Harold W. Horowitz, M.D.

TO THE EDITOR:

The article "Current Concepts Review. Prophylactic Use of Antibiotics for Procedures after Total Joint Replacement" (78-A: 1755-1770, Nov. 1996), by Deacon et al., appears to contain several factual errors.

First, on page 1756, in the section entitled "Dental Procedures," the authors state: "We know of only one randomized placebo-controlled trial confirming the benefits of such prophylaxis in the prevention of late prosthetic-valve endocarditis." The authors then go on to cite a study by Horstkotte et al.3. However, that study was not a randomized placebo-controlled trial. I have read and translated parts of that article from German and have also read an article in English by Horstkotte et al.2 that appears to describe the same research. It is clear from these articles that this was a retrospective clinical study, which is similar in design to a retrospective cohort study. There is no mention of placebos, randomization, or . . . [Full Text of this Article]


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