The Journal of Bone and Joint Surgery 80:725-9 (1998)
© 1998 The Journal of Bone and Joint Surgery, Inc.
Extraskeletal Osteosarcoma of the Hand. A Case Report*
PAUL A. COOK, M.D. ,
MICHAEL S. MURPHY, M.D. ,
PETER C. INNIS, M.D. and
JOSEPH S. YU, M.D. , BALTIMORE, MARYLAND
Investigation performed at Raymond M. Curtis Hand Center, National Center for Treatment of the Hand and Upper Extremity, Union Memorial Hospital, Baltimore
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Introduction
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Osteosarcomas rarely occur in the hand12. This primary neoplasm of bone may be classified, on the basis of its origin, as central, juxtacortical, or extraskeletal. Extraskeletal osteosarcomas are extremely rare and, although their true prevalence is unknown, it has been estimated that they account for approximately one in twenty-five (twenty-six of 6501) reported cases of primary osteosarcoma of bone.
Extraskeletal osteosarcomas are located in the soft tissues without skeletal or periosteal attachment, and they have a uniform sarcomatous pattern and a matrix composed of osteoid or cartilage, or both. In contradistinction to primary osteosarcoma of bone, this variant typically develops after the fourth decade of life1 and the prognosis is uniformly poor1,2,4,5,8,9,11,14,15.
In the present report, we document the clinical and pathological findings in a patient who had an extraskeletal osteosarcoma arising from the thenar muscles of the hand.
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Case Report
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A sixty-three-year-old man was referred to the Raymond . . . [Full Text of this Article]

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