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The Journal of Bone and Joint Surgery 80:607-8 (1998)
© 1998 The Journal of Bone and Joint Surgery, Inc.

Correspondence

Correspondence

Panayiotis J. Papagelopoulos, M.D., J. Eileen Hay, M.D., Evanthia Galanis, M.D., Bernard F. Morrey, M.D., Darryl A. Tannenbaum, M.D., Larry S. Matthews, M.D. and John C. Grady-Benson, M.D.

TO THE EDITOR:

In "Infection around Joint Replacements in Patients Who Have a Renal or Liver Transplantation" (79-A: 36–43, Jan. 1997), Tannenbaum et al. reported, as part of a study predominantly of patients who had had a renal transplantation, the results of joint replacement (two hip and one knee) in three patients who had had a liver transplantation. All three patients who had had a liver transplantation were managed with standard immunosuppression with cyclosporine A and prednisone, with or without azathioprine. A deep infection developed in two of these three patients.

According to Tannenbaum et al., there have been no reports in the literature regarding joint replacement after liver transplantation; there is a high prevalence of devastating infection associated with joint replacement in patients who have had liver transplantation; patients who have had an orthotopic liver transplantation take higher doses of immunosuppressants than those who have had a renal transplantation; . . . [Full Text of this Article]


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