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The Journal of Bone and Joint Surgery 80:262-7 (1998)
© 1998 The Journal of Bone and Joint Surgery, Inc.

Idiopathic Necrosis of Skeletal Muscle in Patients Who Have Diabetes. Report of Four Cases and Review of the Literature*

TIMOTHY A. DAMRON, M.D.{dagger}, E. MARK LEVINSOHN, M.D.{ddagger}, THOMAS M. MCQUAIL, M.D.{dagger}, HAL COHEN, M.D.{dagger}, MICHAEL STADNICK, M.D.{dagger} and MICHELE ROONEY, M.D.{dagger}, SYRACUSE, NEW YORK

Investigation performed at the Departments of Orthopedic Surgery, Radiology, and Pathology, State University of New York at Syracuse, and the Department of Radiology, Crouse Hospital, Syracuse


   Introduction
 
Infarction of skeletal muscle in patients who have diabetes is an infrequently recognized clinicopathological entity1-17. Most of the reports on this condition have appeared in journals and textbooks on internal medicine and radiology. Radiographically, the lesion may be misinterpreted as a soft-tissue sarcoma or infection, in which case the patient may be referred to an orthopaedic surgeon.

The mean age of the four patients reported on here was forty-two years (range, twenty-eight to fifty-nine years). The patients had sought medical attention because of an exquisitely tender swelling of the anterior aspect of the thigh, which had been present for ten days to four weeks before the initial evaluation. Two patients had a history of insulin-dependent diabetes, one had a history of non-insulin-dependent diabetes, and one was diagnosed with diabetes at the time of the initial evaluation. Three patients had no evidence of recurrence after a mean duration of follow-up . . . [Full Text of this Article]


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