The Journal of Bone and Joint Surgery 80:1554 (1998)
© 1998 The Journal of Bone and Joint Surgery, Inc.
Correspondence
Jonathan Cohen, M.D.,
Joshua J. Jacobs, M.D.,
Robert M. Urban and
Jeremy L. Gilbert, Ph.D.
TO THE EDITOR:
One of the issues relating to the corrosion of orthopaedic implants that was not mentioned in "Current Concepts Review. Corrosion of Metal Orthopaedic Implants" (80-A: 268282, Feb. 1998), by Jacobs et al., is the profound difference between the corrosion that occurs when implants are in contact with aqueous solutions in vitro and the corrosion that occurs in vivo. The crux of the difference has to do with how the energy released by the chemical reactions affects the elements in proximity to the implant, such as the film of fluid (exudate or transudate) between the implant and the fibrous, osseous, or marrow tissue of the host. The energy from well tolerated implants may be insufficient to incite substantial inflammation (which perhaps defines the term tolerated). The energy may well be cumulative and, over months or years, may be responsible for the failure of the implant due to corrosion.
. . . [Full Text of this Article]

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