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The Journal of Bone and Joint Surgery (American) 80:104-10 (1998)
© 1998 The Journal of Bone and Joint Surgery, Inc.

Non-Hodgkin Lymphoma of the Spine. A Report of Three Cases with a Minimum Ten-Year Follow-up*

JOHN J. VAUGHAN, M.D.{dagger}, ROBERT B. WINTER, M.D.{ddagger}, JOHN E. LONSTEIN, M.D.{ddagger}, JOHN R. JOHNSON, M.D.§ and JAMES E. DUNNINGTON, M.D.#, MINNEAPOLIS, MINNESOTA

Investigation performed at Minnesota Spine Center, Minneapolis

The first 150 words of the full text of this article appear below.

Primary non-Hodgkin lymphoma of bone is histologically identical to other lymphomas but arises initially as a localized bone lesion. Malignant lymphoma of bone apparently was first described by Wieland in 1901. Oberling and Raileanu, in 1932, characterized these tumors as reticulum cell sarcomas of bone and distinguished them from Ewing sarcomas. Non-Hodgkin lymphoma of bone is rare. In a study by Freeman et al., it represented less than 5 per cent (sixty-nine) of 1467 extranodal non-Hodgkin lymphomas. Mirra reported that the lesion rarely occurs as a primary bone tumor. Most authors have reported that lymphomas of bone are more common in the appendicular skeleton than in the axial skeleton. Parker and Jackson noted that these tumors have a predilection for the long bones and the over-all prognosis is favorable. However, Craver and Copeland reported on seventeen patients who had lymphosarcoma and found that the spine and the pelvis were involved . . . [Full Text of this Article]


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