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The Journal of Bone and Joint Surgery 79:1270-1 (1997)
© 1997 The Journal of Bone and Joint Surgery, Inc.

Correspondence

Correspondence

A. J. G. Swaak, M.D., Ph.D., Dev K. Mishra, M.D., Mary C. Schmitz, M.S., Richard L. Lieber, Ph.D. and Jan Fridén, M.D., Ph.D.

TO THE EDITOR:

In the article "Anti-Inflammatory Medication after Muscle Injury. A Treatment Resulting in Short-Term Improvement but Subsequent Loss of Muscle Function" (77-A: 1510–1519, Oct. 1995), Mishra et al. claimed that although anti-inflammatory medication after muscle injury results in a short-term improvement, there is subsequent loss of muscle function. In the Abstract, they concluded that their "results may prompt rethinking of the liberal prescription of non-steroidal anti-inflammatory drugs as treatment for muscle injury."

This conclusion is misleading and was not supported by the results obtained. First, it is incorrect to speak of non-steroidal anti-inflammatory drugs in general when only one example of the phenylpropionic acid compounds was examined. The effects of compounds of the arylalkanoic class in this model of exercise-induced injury, compared with those of compounds of other non-steroidal anti-inflammatory drug classes, must still be determined. Non-steroidal anti-inflammatory drugs can be classified on the basis of their chemical . . . [Full Text of this Article]


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