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The Journal of Bone and Joint Surgery 79:1119-20 (1997)
© 1997 The Journal of Bone and Joint Surgery, Inc.

Editorial

Editorial - The Prospective, Randomized, Double-Blind Clinical Trial in Orthopaedic Surgery

Charles R. Clark, M.D.

Deputy Editor for Adult Reconstruction

This issue of The Journal contains an important article entitled "Resurfacing of the Patella in Total Knee Arthroplasty. A Prospective, Randomized, Double-Blind Study," by Barrack et al. This study is important not only from the standpoint of its findings but also from the standpoint of its methodology.

Most reports in the orthopaedic literature relating to operative procedures are retrospective reviews of series of patients. Indeed, very valuable information can be, and is, obtained from these studies. However, retrospective studies have certain limitations, including, in many instances, the inability to control for many variables because of the lack of specific criteria for inclusion and exclusion. A prospective, randomized, double-blind study, with the careful use of criteria for inclusion and exclusion, allows the investigators to minimize the number of variables that they are analyzing. No word is perhaps more important in the field of statistics than the word random. An item is . . . [Full Text of this Article]


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