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The Journal of Bone and Joint Surgery 79:911-6 (1997)
© 1997 The Journal of Bone and Joint Surgery, Inc.

Sclerotic Lesion of the Tibia without Involvement of Lymph Nodes. Report of an Unusual Case of Rosai-Dorfman Disease*

FRANCIS R. PATTERSON, M.D.{dagger}, MICHELE T. ROONEY, M.D.{dagger}, TIMOTHY A. DAMRON, M.D.{dagger}, ANDREI I. VERMONT, M.D.{dagger} and ROBERT E. HUTCHISON, M.D.{dagger}, SYRACUSE, NEW YORK

Investigation performed at the Departments of Orthopedic Surgery, Pathology, and Radiology, State University of New York Health Science Center, Syracuse


   Introduction
 
Rosai-Dorfman disease, or sinus histiocytosis with massive lymphadenopathy, was first described in 1969 and is characterized by widespread adenopathy, fever, leukocytosis, an elevated sedimentation rate, and hypergammaglobulinemia12,13. Since 1969, extranodal involvement has been noted in 182 of the 423 patients in the registry of Rosai-Dorfman disease2,16. Osseous involvement is typically lytic and was observed in thirty-three of the 423 patients in the registry2. We report on a patient who was first seen because of symptoms due to a predominately sclerotic tibial lesion but who had no evidence of lymphadenopathy, a characteristic of Rosai-Dorfman disease.


   Case Report
 
A seventeen-year-old black boy sustained a hyperextension injury of the left knee while playing in a high-school football game in September 1994. He was able to continue playing and did not notice any swelling about the knee until three days after the injury. He completed the football season, but he reported intermittent swelling . . . [Full Text of this Article]


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S.-Y. Loh, K.-B. Tan, Y.-S. Wong, and Y.-S. Lee
Rosai-Dorfman Disease of the Triquetrum Without Lymphadenopathy. A Case Report
J. Bone Joint Surg. Am., March 1, 2004; 86(3): 595 - 598.
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