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The Journal of Bone and Joint Surgery 79:263-76 (1997)
© 1997 The Journal of Bone and Joint Surgery, Inc.

Current Concepts Review

Current Concepts Review - Injury of an Extremity as a Risk Factor for the Development of Osteoporosis*

MARKKU JÄRVINEN, M.D., PH.D.{dagger} and PEKKA KANNUS, M.D., PH.D.{ddagger}, TAMPERE, FINLAND

Investigation performed at the Section of Orthopaedics, Department of Surgery, Tampere University Hospital, and the Accident and Trauma Research Center, Urho Kaleva Kekkonen Institute for Health Promotion Research, Tampere


   Introduction
 
Low bone mass occurs with a relatively high prevalence in the elderly population and is thought to be a natural part of aging. When low bone mass is associated with architectural deterioration of the bone, decreased bone strength, and increased susceptibility to fractures, the condition is called osteoporosis77. Osteoporotic fractures are a major public-health problem not only because of the associated morbidity and mortality but also because of the health-care costs that they generate. The number and rate of fractures of the hip have increased in developed countries worldwide during recent decades, and they are expected to rise dramatically as the populations age12,34,67.

The two most important risk factors for osteoporosis are an insufficient bone mass by the time of skeletal maturity (low peak bone mass) and the rapid loss of bone that occurs in some women after menopause6,9-11. The average lifetime bone loss after the acquisition . . . [Full Text of this Article]


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