The Journal of Bone and Joint Surgery 79:1849-53 (1997)
© 1997 The Journal of Bone and Joint Surgery, Inc.
Osteosarcoma Associated with Osteochondritis Dissecans. A Case Report and Review of the Literature*
WON-JONG BAHK, M.D. ,
EARL W. BRIEN, M.D. and
JOSEPH M. MIRRA, M.D. , LOS ANGELES, CALIFORNIA
Investigation performed at the Division of Orthopaedic Oncology, Orthopaedic Hospital, Los Angeles
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Introduction
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Sarcoma associated with a bone infarct is fairly unusual; we are aware of only forty-nine well documented cases (in forty-seven patients)1-10,12-20. Of these forty-nine tumors, thirty were malignant fibrous histiocytomas; nine, osteosarcomas; five, fibrosarcomas; three, angiosarcomas; and two, poorly differentiated sarcomas. All occurred in a non-epiphyseal region of a long bone. In the present report, we describe the case of an elderly woman in whom an osteosarcoma was found incidentally on examination of bone that had been removed to perform a total knee replacement. The osteosarcoma was located within an area of osteochondritis dissecans in the medial femoral condyle. To our knowledge, we are the first to report a sarcoma arising from an area of osteochondritis dissecans.
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Case Report
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A sixty-seven-year-old white woman had had increasing pain in the right knee for several months. There was only minimum relief of pain after the administration of non-steroidal anti-inflammatory medications and an injection . . . [Full Text of this Article]

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