This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Letters to the Editor: Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when Letters to the Editor are posted
Right arrow Alert me if a correction is posted
Services
Right arrow E-mail this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My File Cabinet
Right arrow Download to citation manager
Right arrowReprints and Permissions
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Linville, D.
Right arrow Articles by Librojo, E.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Linville, D.
Right arrow Articles by Librojo, E.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us   Add to Technorati  
What's this?
The Journal of Bone and Joint Surgery 78:967-8 (1996)
© 1996 The Journal of Bone and Joint Surgery, Inc.

Correspondence

Correspondence

Douglas Linville, M.D., Robert J. Fragen, M.D., S. David Stulberg, M.D., Richard Wixson, M.D., Silas Glisson, Ph.D. and Eleanor Librojo, R.N.

TO THE EDITOR:

I read the article "Effect of Ketorolac Tromethamine on Bleeding and on Requirements for Analgesia after Total Knee Arthroplasty" (77-A: 998–1002, July 1995), by Fragen et al., with great interest. I find it hopeful that excellent analgesia can be obtained with a non-opiate substance in order to limit side effects in an often elderly population at risk for complications. I am still concerned, however, about bleeding and wound complications in the total joint population. These very important complications, which may prove catastrophic, were not addressed in this study.

As we know from the literature regarding prophylactic therapy with low-dose warfarin and low-molecular-weight heparin, substantial bleeding episodes occur in as many as 5 per cent of treated patients2,4. In these reports, a major bleeding episode was defined as a decrease in hemoglobin of 0.002 gram per deciliter or more, the need for a transfusion of two units . . . [Full Text of this Article]


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us   Add to Technorati Technorati    What's this?