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Journal of Bone and Joint Surgery, 1927;9:67-78.
© 1927 by The Journal of Bone and Joint Surgery, Inc

REGENERATION OF THE SYNOVIAL MEMBRANE FOLLOWING TYPICAL SYNOVECTOMY

W. EUGENE WOLCOTT M.D., F.A.C.S.

1. Synovial membrane does regenerate after typical synovectomy.

2. The regenerated pouch closely simulates the normal in size, contour, histological structure and function.

3. The newly formed pouch is the result of connective tissue metaplasia.

4. Connective tissue metaplasia is progressive until about the fourth week when the synovial membrane has been reformed. With this completed, the stimulus for new growth is removed and the fibroblastic cells mature into normal connective tissue.

5. That there is an inhibition of progressive metaplasia after the new synovial membrane is formed, explains the absence of excessive scar tissue formation as well as the permanency of restored function.


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