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Journal of Bone and Joint Surgery, 1927;9:111-118.
© 1927 by The Journal of Bone and Joint Surgery, Inc

PECULIAR BEHAVIOR OF GIANT-CELL TUMORS

C. C. CHATTERTON M.D. and A. E. FLAGSTAD M.D.

Case 1 suggests that occasionally true giant-cell tumors do undergo malignant changes even where operative interference and trauma have been mild.

Case 2 illustrates the borderline aggressive type of giant-cell tumor. Clinically and roentgenologically this was more suggestive of malignancy than Case 1. Microscopically the tumor is benign.

These cases with others reported, suggest that at times difficulty and peculiarity is encountered in the diagnosis and behavior of giant-cell tumors.


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