The Journal of Bone and Joint Surgery (American). 2006;88:48-55.
doi:10.2106/JBJS.F.00538
© 2006 The Journal of Bone and Joint Surgery, Inc.
Survivorship Analysis and Radiographic Outcome Following Tantalum Rod Insertion for Osteonecrosis of the Femoral Head
Christian J.H. Veillette, MD, FRCS(C), MSc, BSc(Hon),
Hossein Mehdian, MD,
Emil H. Schemitsch, MD, FRCS(C) and
Michael D. McKee, MD, FRCS(C)
Corresponding author: Michael D. McKee, MD, FRCS(C) Division of
Orthopaedic Surgery, Department of Surgery, University of Toronto, St.
Michael's Hospital, 55 Queen Street East, Suite 800, Toronto, ON M5C 1R6,
Canada. E-mail address:
mckeem{at}smh.toronto.on.ca
The authors did not receive grants or outside funding in support of their
research for or preparation of this manuscript. One or more of the authors
received payments or other benefits or a commitment or agreement to provide
such benefits from a commercial entity (Zimmer, Inc.). No commercial entity
paid or directed, or agreed to pay or direct, any benefits to any research
fund, foundation, educational institution, or other charitable or nonprofit
organization with which the authors are affiliated or associated.
Background: For early stages of osteonecrosis, preservation of the
femoral head is the primary objective; however, there has not been a consensus
on how best to achieve this goal. Core decompression alone is associated with
a lack of structural support with inconsistent outcomes, whereas vascularized
fibular grafting requires an extensive surgical procedure with high donor-site
morbidity and prolonged rehabilitation. The adjunctive use of a porous
tantalum implant offers the advantages of core decompression, structural
support, minimally invasive surgery, and no donor-site morbidity. The purpose
of this study was to assess the survivorship and to evaluate the clinical
results and radiographic outcomes of hips in which osteonecrosis of the
femoral head was treated with core decompression and a porous tantalum
implant.
Methods: We evaluated fifty-four patients (sixty consecutive hips)
in whom osteonecrosis of the femoral head was treated with core decompression
and insertion of a porous tantalum implant. Fifty-two patients (fifty-eight
hips) were available for follow-up at a mean of twenty-four months. All
patients were sixty-five years of age or younger (mean age, thirty-five
years). According to the classification system of Steinberg et al., one hip
(2%) had stage-I disease, forty-nine hips (84%) had stage-II disease, and
eight hips (14%) had stage-III disease. Outcome measures that were used
included a limb-specific score (Harris hip score), radiographic outcome
measures, and survivorship analysis with revision to total hip arthroplasty as
the end point.
Results: Overall, nine hips (15.5%) were converted to total hip
arthroplasty, including six with stage-II disease and three with stage-III
disease. The overall survival rates were 91.8% (95% confidence interval, 87.8%
to 95.8%) at twelve months, 81.7% (95% confidence interval, 75.8% to 87.6%) at
twenty-four months, and 68.1% (95% confidence interval, 54.7% to 81.5%) at
forty-eight months. The absence of chronic systemic diseases resulted in a
survival rate of 92% at forty-eight months (95% confidence interval, 87.4% to
96.4%).
Conclusions: Treatment of early stage osteonecrosis of the femoral
head with core decompression and a porous tantalum implant can be accomplished
with a minimally invasive technique and no donor-site morbidity. The early
clinical results show encouraging survival rates in patients who do not have
chronic systemic disease, especially in association with early stage
disease.
Level of Evidence: Therapeutic Level IV. See Instructions
to Authors on
jbjs.org for a
complete description of levels of evidence.

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Letters to the Editor:
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- The Treatment of Early Stage Osteonecrosis
- James K. Brannon, M.D.
- JBJS Online, 11 Jan 2007
[Full text]
- Dr. McKee, et al. respond to Dr. Brannon
- Michael McKee, M.D., FRCS(C), et al.
- JBJS Online, 11 Jan 2007
[Full text]
- The Treatment of ONFH Must Include Relief of Pain
- James K. Brannon, M.D.
- JBJS Online, 23 Jan 2007
[Full text]
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