The Journal of Bone and Joint Surgery (American) 86:1998-2003 (2004)
© 2004 The Journal of Bone and Joint Surgery, Inc.
Clinical and Radiographic Results Associated with a Modern, Cementless Modular Cup Design in Total Hip Arthroplasty
Alejandro González Della Valle, MD1,
Adriana Zoppi, MD2,
Margaret G.E. Peterson, PhD1 and
Eduardo A. Salvati, MD1
1 The Hospital for Special Surgery, 535 East 70th Street, New York, NY 10021.
E-mail address for E.A. Salvati:
salvatie{at}hss.edu
2 Department of Orthopaedics, Civil Hospital of Velletri-RMH, Rome, Italy
Investigation performed at the Hospital for Special Surgery, New York,
NY
In support of their research or preparation of this manuscript, one or more
of the authors received grants or outside funding from Zimmer. None of the
authors received payments or other benefits or a commitment or agreement to
provide such benefits from a commercial entity. No commercial entity paid or
directed, or agreed to pay or direct, any benefits to any research fund,
foundation, educational institution, or other charitable or nonprofit
organization with which the authors are affiliated or associated.
Background: First-generation cementless modular cups reproducibly
achieved fixation to bone but were associated with unacceptable rates of
pelvic osteolysis and mechanical failure. Consequently, second-generation cups
were developed with shells that had a limited number of holes (or no holes) as
well as improved locking mechanisms, a polished inner surface, and increased
conformity with the liner. The purpose of the present study was to evaluate
the clinical and radiographic results associated with the use of a
second-generation acetabular component for primary total hip arthroplasty.
Methods: Two hundred and ninety-seven patients underwent 335
consecutive primary total hip arthroplasties that were performed by a single
surgeon with a second-generation modular acetabular component. All cups were
implanted with a press-fit technique. Ten patients were lost to follow-up, and
sixteen died from unrelated causes. The remaining 271 patients (308 hips) were
followed clinically (with the Hospital for Special Surgery hip-scoring system)
and radiographically for four to seven years.
Results: One cup was revised because of aseptic loosening. There
were seven additional revisions: five were performed because of aseptic
loosening of the stem with a well-fixed cup, and two were performed because of
deep infection. Among the 271 patients who were alive at the time of the last
follow-up, 266 (98%) had retention of the cup and 264 (97%) had retention of
both components with a good or excellent clinical result. In the group of 229
patients (262 hips) with complete radiographic follow-up, 259 cups were well
fixed and the average wear rate (for the 246 hips for which this rate could be
calculated) was 0.09 mm/yr. Osteolysis was detected in twelve hips (5%) and
was associated with male gender (p = 0.001) and the annual wear rate (p =
0.004). The extent of calcar resorption was also associated with the annual
wear rate (p < 0.001).
Conclusions: This second-generation acetabular cup design
predictably achieved bone fixation and was associated with low rates of
revision for loosening and osteolysis after intermediate-term follow-up.
Level of Evidence: Therapeutic study, Level IV (case
series [no, or historical, control group]). See Instructions to Authors for a
complete description of levels of evidence.

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