The Journal of Bone and Joint Surgery (American). 2004;86:2666-2670
© 2004 The Journal of Bone and Joint Surgery, Inc.
The Double-Density Sign: A Radiographic Finding Suggestive of an Os Acromiale
Donald H. Lee, MD1,
Kwan H. Lee, MD2,
Robert Lopez-Ben, MD3 and
Edwin L. Bradley, PhD4
1 Division of Orthopedic Surgery, University of Alabama at Birmingham, 905
Faculty Office Tower, 1530 Third Avenue South, Birmingham, AL 35294-3409.
E-mail address:
donald.lee{at}ortho.uab.edu
2 899 Alford Avenue, Birmingham, AL 35226
3 Department of Radiology, University of Alabama at Birmingham, JTN 368, 619
19th Street South, Birmingham, AL 35294
4 Department of Biostatistics, University of Alabama at Birmingham, 1665
University Boulevard, RPHB Room 327, Birmingham, AL 35294-0022
Investigation performed at the Division of Orthopedic Surgery,
University of Alabama at Birmingham, Birmingham, Alabama
The authors did not receive grants or outside funding in support of their
research or preparation of this manuscript. They did not receive payments or
other benefits or a commitment or agreement to provide such benefits from a
commercial entity. No commercial entity paid or directed, or agreed to pay or
direct, any benefits to any research fund, foundation, educational
institution, or other charitable or nonprofit organization with which the
authors are affiliated or associated.
Background: An os acromiale results from the failure of fusion of
the acromial secondary centers of ossification. It is most easily seen
radiographically on an axillary lateral view. The purpose of the present study
was to describe two simple radiographic findings, the double-density sign on a
standard anteroposterior view of the shoulder and a cortical irregularity
found on a supraspinatus outlet view, that are highly suggestive of an os
acromiale.
Methods: Anteroposterior, axillary lateral, and supraspinatus outlet
radiographs of thirty-four shoulders in thirty adult patients with an os
acromiale were reviewed by two independent observers and were compared with
those of a control group of thirty-one shoulders in twenty-nine patients
without an os acromiale. Statistical analysis was performed with use of a
generalized logistic regression model to determine if an os acromiale could be
detected on all three radiographic views. A kappa analysis was performed to
determine interobserver reliability.
Results: In the group with an os acromiale, twenty-eight shoulders
had a meso-acromion and six had a pre-acromion. A double-density sign was
noted on the anteroposterior radiograph of 82.4% of the shoulders, an os
acromiale was noted on the axillary lateral radiograph of 95.6% of the
shoulders, and a cortical irregularity was noted on the supraspinatus outlet
radiograph of 75.8% of the shoulders. In the control group, a double-density
sign was noted on the anteroposterior radiograph of 4.8% of the shoulders, no
os acromiale was seen on the axillary lateral radiograph of any of the
shoulders, and a cortical irregularity was noted on the supraspinatus outlet
radiograph of one shoulder. These differences between the os acromiale and
control groups were significant (p < 0.0001). The overall sensitivities of
the anteroposterior, axillary, and supraspinatus outlet views for the
detection of an os acromiale were 82.4%, 94.1%, and 73.5%, respectively. The
overall specificities of the three views were 95.2%, 100%, and 98.4%,
respectively. The interobserver reliabilities of the three views were 0.66,
0.88, and 0.7, respectively (p < 0.0001).
Conclusions: The double-density sign on a standard anteroposterior
radiograph of the shoulder and a cortical irregularity on the supraspinatus
outlet view are highly suggestive of an os acromiale. An os acromiale should
be suspected in a patient with these radiographic findings.
Level of Evidence: Diagnostic study, Level IV-1
(case-control study). See Instructions to Authors for a complete description
of levels of evidence.

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