The Journal of Bone and Joint Surgery (American) 85:2325-2331 (2003)
© 2003 The Journal of Bone and Joint Surgery, Inc.
Comparison of the Wear Rates of Twenty-eight and Thirty-two-Millimeter Femoral Heads on Cross-Linked Polyethylene Acetabular Cups in a Wear Simulator
Juan C. Hermida, MD1,
Arnie Bergula, BS1,
Peter Chen, PhD1,
Clifford W. Colwell, Jr., MD1 and
Darryl D. D'Lima, MD1
1 Scripps Clinic, 11025 North Torrey Pines Road, Suite 140, La Jolla, CA 92037.
E-mail address for C.W. Colwell Jr.:
colwell{at}scripps.edu
Investigation performed at the Orthopaedic Research Laboratories,
Scripps Clinic Center for Orthopaedic Research and Education, La Jolla,
California
In support of their research or preparation of this manuscript, one or more
of the authors received grants or outside funding from Howmedica Osteonics.
None of the authors received payments or other benefits or a commitment or
agreement to provide such benefits from a commercial entity. No commercial
entity paid or directed, or agreed to pay or direct, any benefits to any
research fund, foundation, educational institution, or other charitable or
nonprofit organization with which the authors are affiliated or
associated.
Background: The use of larger femoral head sizes in total hip
arthroplasty has been shown to reduce the rate of dislocation and to increase
the range of motion; however, such components have been associated with
unacceptably high polyethylene wear rates. Studies have shown dramatic
differences in wear rates between nominally cross-linked polyethylene (i.e.,
polyethylene that is cross-linked during radiation sterilization) and elevated
cross-linked polyethylene (i.e., polyethylene that is cross-linked to a higher
degree than that obtained by radiation sterilization alone). The aim of this
study was to test the effect of increased cross-linking and of increased head
size on polyethylene wear rates.
Methods: Four groups of acetabular liners obtained from a single
manufacturer, including 28-mm-diameter nominally cross-linked, 32-mm-diameter
nominally cross-linked, 28-mm-diameter elevated cross-linked, and
32-mm-diameter elevated cross-linked polyethylene liners, were tested. Three
implants from each group were tested in a twelve-station hip wear simulator
with use of 90% bovine serum as a lubricant. The liners were articulated with
the appropriately sized cobalt-chromium femoral head. Additional liners from
each design were subjected only to the same load without motion to serve as
load-soak controls to account for any weight gain due to fluid absorption.
Gravimetric analysis was performed every 500,000 cycles for a total of five
million cycles.
Results: Nominally cross-linked liners demonstrated mean wear rates
of 14.97 and 16.92 mg per million cycles for the 28-mm and 32-mm head sizes,
respectively. Both of the elevated cross-linked liners had significantly lower
wear rates than the nominally cross-linked liners, with a mean of 1.51 and
2.57 mg per million cycles for the 28-mm and 32-mm head sizes, respectively (p
< 0.001).
Conclusion and Clinical Relevance: The dramatic reduction in wear
rates with polyethylene cross-linking, even with the larger head size, may
increase the potential for use of 32-mm head components in total hip
arthroplasty.

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