This Article
Right arrow Full Text Free
Right arrow Full Text (PDF) Free
Right arrow Letters to the Editor: Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when Letters to the Editor are posted
Right arrow Alert me if a correction is posted
Services
Right arrow E-mail this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My File Cabinet
Right arrow Download to citation manager
Right arrow Rights and Permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by PROCTOR, C. S.
Right arrow Articles by SIMON, T. M.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by PROCTOR, C. S.
Right arrow Articles by SIMON, T. M.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us   Add to Facebook   Add to Technorati   Add to Twitter  
What's this?
The Journal of Bone and Joint Surgery 79:997-1006 (1997)
© 1997 The Journal of Bone and Joint Surgery, Inc.

Characterization of the Repair Tissue after Removal of the Central One-Third of the Patellar Ligament. An Experimental Study in a Goat Model*

CHRISTOPHER S. PROCTOR, M.D.{dagger}, DOUGLAS W. JACKSON, M.D.{ddagger} and TIMOTHY M. SIMON, M.S.{ddagger}, LONG BEACH, CALIFORNIA

Investigation performed at the Orthopaedic Research Institute at the Southern California Center for Sports Medicine and Long Beach Memorial Medical Center, Long Beach

The purpose of this study was to characterize the repair tissue that develops after removal of a portion of the patellar ligament for use as a graft. A six-millimeter-wide strip was obtained from the central portion of the patellar ligament with tibial and patellar bone plugs from one knee (stifle joint) of eight goats. The repair tissue that formed in the defect was characterized in terms of its structural, material, histological, and ultrastructural properties twenty-one months after the operation. The contralateral patellar ligament served as a control. Representative specimens were taken from the proximal, middle, and distal portions of the repair tissue and the control tissue for histological study and examination with transmission electron microscopy. The six-millimeter-long defect filled with repair tissue that increased the cross-sectional area by a mean of 42 per cent compared with the control values (p < 0.05). The maximum force to failure and the ultimate stress of the repair tissue were significantly decreased (by a mean of 51 and 65 per cent, respectively) compared with those of the controls (p < 0.001 for both). The stiffness also was reduced, by a mean of 27 per cent, but this was not significant (p > 0.05). Magnetic resonance imaging of the donor site showed slightly increased signal intensity compared with the intensity on the control side. Histological sections from the donor site contained collagenous (scar) tissue that was less organized, more cellular, and more vascular than the control tissue. Evaluation of the ultrastructure revealed that the repair tissue was composed primarily of collagen fibrils with a small diameter (range, fifty to 100 nanometers). CLINICAL RELEVANCE: The results of the present study suggest that the repair tissue that develops after removal of a strip of the patellar ligament for use as a graft is not comparable with normal tissue in terms of its structural, material, histological, and ultrastructural properties by twenty-one months. This should be kept in mind when this repair tissue is considered for use as a graft for revision of a reconstruction of the anterior cruciate ligament.


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us   Add to Facebook Facebook   Add to Technorati Technorati   Add to Twitter Twitter    What's this?


This article has been cited by other articles:


Home page
 Am J Sports MedHome page
K. T. Jensen, D. P. Rabago, T. M. Best, J. J. Patterson, and R. Vanderby Jr
Response of Knee Ligaments to Prolotherapy in a Rat Injury Model
Am. J. Sports Med., July 1, 2008; 36(7): 1347 - 1357.
[Abstract] [Full Text] [PDF]

Home page
 Am J Sports MedHome page
M. Liden, T. Movin, L. Ejerhed, N. Papadogiannakis, E. Blomen, K. Hultenby, and J. Kartus
A Histological and Ultrastructural Evaluation of the Patellar Tendon 10 Years After Reharvesting Its Central Third
Am. J. Sports Med., April 1, 2008; 36(4): 781 - 788.
[Abstract] [Full Text] [PDF]

Home page
 Am J Sports MedHome page
M. Svensson, T. Movin, L. Rostgard-Christensen, E. Blomen, K. Hultenby, and J. Kartus
Ultrastructural Collagen Fibril Alterations in the Patellar Tendon 6 Years After Harvesting Its Central Third
Am. J. Sports Med., February 1, 2007; 35(2): 301 - 306.
[Abstract] [Full Text] [PDF]

Home page
 J Am Acad Orthop SurgHome page
R. V. West and C. D. Harner
Graft Selection in Anterior Cruciate Ligament Reconstruction
J. Am. Acad. Ortho. Surg., May 1, 2005; 13(3): 197 - 207.
[Abstract] [Full Text] [PDF]

Home page
 Am J Sports MedHome page
S. S. Gill, M. A. Turner, T. C. Battaglia, H. T. Leis, G. Balian, and M. D. Miller
Semitendinosus Regrowth: Biochemical, Ultrastructural, and Physiological Characterization of the Regenerate Tendon
Am. J. Sports Med., July 1, 2004; 32(5): 1173 - 1181.
[Abstract] [Full Text] [PDF]

Home page
 Am J Sports MedHome page
A. J. Colosimo, R. S. Heidt Jr, J. A. Traub, and R. L. Carlonas
Revision Anterior Cruciate Ligament Reconstruction with a Reharvested Ipsilateral Patellar Tendon
Am. J. Sports Med., November 1, 2001; 29(6): 746 - 750.
[Abstract] [Full Text] [PDF]

Home page
 Am J Sports MedHome page
J. Kartus, T. Movin, N. Papadogiannakis, L. R. Christensen, S. Lindahl, and J. Karlsson
A Radiographic and Histologic Evaluation of the Patellar Tendon after Harvesting Its Central Third
Am. J. Sports Med., March 1, 2000; 28(2): 218 - 226.
[Abstract] [Full Text] [PDF]