The Journal of Bone and Joint Surgery 78:204-11 (1996)
© 1996 The Journal of Bone and Joint Surgery, Inc.
Donor-Site Morbidity with Use of Vascularized Autogenous Fibular Grafts*
T. PARKER VAIL, M.D. and
JAMES R. URBANIAK, M.D. , DURHAM, NORTH CAROLINA
Investigation performed at Duke University Medical Center, Durham
One hundred and ninety-eight consecutive patients (247 vascularized fibular grafts) were studied to determine the prevalence of morbidity at the donor site after the grafts had been obtained. Objective motor weakness, subjective discomfort in the ankle and other sites in the leg, and sensory abnormalities in the lower limb (or limbs) from which the graft had been obtained were recorded. The average duration of follow-up was forty-seven months (range, twenty-four to 144 months). Kaplan-Meier analysis was used to estimate the prevalence of each finding for the entire cohort over time.
Forty-seven (19.0 per cent) of the 247 lower limbs had at least one of the findings, and eighteen (24.3 per cent) of the seventy-four limbs for which data were available at five years or more had findings at that time. Twenty-five (10.1 per cent) of the 247 limbs had evidence of motor weakness at three months postoperatively, although no limb had this finding subsequently. At five years or more postoperatively, the prevalence had decreased to two (2.7 per cent) of the seventy-four limbs. Twelve (4.9 per cent) of the 247 limbs had sensory deficits at three months; this increased to 11.8 per cent (95 per cent confidence interval, 7.7 to 17.7 per cent), according to the Kaplan-Meier analysis, at five years. Pain at sites other than the ankle was noted in nine (3.6 per cent) of the 247 limbs at three months and in 8.9 per cent (95 per cent confidence interval, 5.5 to 14.1 per cent), according to the Kaplan-Meier analysis, at five years. The prevalence of pain in the ankle also increased with time, from four (1.6 per cent) of the 247 limbs at three months to 11.5 per cent (95 per cent confidence interval, 7.4 to 17.6 per cent), according to the Kaplan-Meier analysis, at five years.
Removal of a vascularized portion of the fibula is associated with a low prevalence of motor weakness and sensory deficits in the foot. The prevalence of pain in the ankle and lower limb increases with time, with some patients having a late onset of the symptoms. While free vascularized fibular grafts remain ideal for many applications, the morbidity must be weighed against the benefits.

CiteULike Connotea Del.icio.us Technorati What's this?
This article has been cited by other articles:

|
 |

|
 |
 
M. Tanzer, J.D. Bobyn, J.J. Krygier, and D. Karabasz
Histopathologic Retrieval Analysis of Clinically Failed Porous Tantalum Osteonecrosis Implants
J. Bone Joint Surg. Am.,
June 1, 2008;
90(6):
1282 - 1289.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
C. J.H. Veillette, H. Mehdian, E. H. Schemitsch, and M. D. McKee
Survivorship Analysis and Radiographic Outcome Following Tantalum Rod Insertion for Osteonecrosis of the Femoral Head
J. Bone Joint Surg. Am.,
November 1, 2006;
88(suppl_3):
48 - 55.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
M. A. Mont, L. C. Jones, and D. S. Hungerford
Nontraumatic Osteonecrosis of the Femoral Head: Ten Years Later
J. Bone Joint Surg. Am.,
May 1, 2006;
88(5):
1117 - 1132.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
J. A. Wilden, S. L. Moran, M. B. Dekutoski, A. T. Bishop, and A. Y. Shin
Results of Vascularized Rib Grafts in Complex Spinal Reconstruction
J. Bone Joint Surg. Am.,
April 1, 2006;
88(4):
832 - 839.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
S. B. Keizer, N. B. Kock, P. D. S. Dijkstra, A. H. M. Taminiau, and R. G. H. H. Nelissen
Treatment of avascular necrosis of the hip by a non-vascularised cortical graft
J Bone Joint Surg Br,
April 1, 2006;
88-B(4):
460 - 466.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
D. Marciniak, C. Furey, and J. W. Shaffer
Osteonecrosis of the Femoral Head. A Study of 101 Hips Treated with Vascularized Fibular Grafting
J. Bone Joint Surg. Am.,
April 1, 2005;
87(4):
742 - 747.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
K. N. Malizos, C. G. Zalavras, P. N. Soucacos, A. E. Beris, and J. R. Urbaniak
Free Vascularized Fibular Grafts for Reconstruction of Skeletal Defects
J. Am. Acad. Ortho. Surg.,
September 1, 2004;
12(5):
360 - 369.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
P. E. Beaule and H. C. Amstutz
Management of Ficat Stage III and IV Osteonecrosis of the Hip
J. Am. Acad. Ortho. Surg.,
March 1, 2004;
12(2):
96 - 105.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
T. A. DeCoster, R. J. Gehlert, E. A. Mikola, and M. A. Pirela-Cruz
Management of Posttraumatic Segmental Bone Defects
J. Am. Acad. Ortho. Surg.,
January 1, 2004;
12(1):
28 - 38.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
L. L. Pacelli, J. Gillard, S. W. McLoughlin, and M. J. Buehler
A Biomechanical Analysis of Donor-Site Ankle Instability Following Free Fibular Graft Harvest
J. Bone Joint Surg. Am.,
March 31, 2003;
85(4):
597 - 603.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
J. R. Lieberman, D. J. Berry, M. A. Montv, R. K. Aaron, J. J. Callaghan, A. Rayadhyaksha, and J. R. Urbaniak
Osteonecrosis of the Hip: Management in the Twenty-first Century
J. Bone Joint Surg. Am.,
May 1, 2002;
84(5):
834 - 853.
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
S. E. Emery
Cervical Spondylotic Myelopathy: Diagnosis and Treatment
J. Am. Acad. Ortho. Surg.,
November 1, 2001;
9(6):
376 - 388.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
N. A. Ebraheim, H. Elgafy, and R. Xu
Bone-Graft Harvesting From Iliac and Fibular Donor Sites: Techniques and Complications
J. Am. Acad. Ortho. Surg.,
May 1, 2001;
9(3):
210 - 218.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
M. Shindo, B. P. Fong, G. F. Funk, and L. H. Karnell
The Fibula Osteocutaneous Flap in Head and Neck Reconstruction: A Critical Evaluation of Donor Site Morbidity
Arch Otolaryngol Head Neck Surg,
December 1, 2000;
126(12):
1467 - 1472.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
S. P. SCULLY, R. K. AARON, and J. R. URBANIAK
Survival Analysis of Hips Treated with Core Decompression or Vascularized Fibular Grafting Because of Avascular Necrosis
J. Bone Joint Surg. Am.,
September 1, 1998;
80(9):
1270 - 1275.
[Abstract]
[Full Text]
|
 |
|
|