The Journal of Bone and Joint Surgery, Vol 77, Issue 3 340-345, Copyright © 1995 by Journal of Bone and Joint Surgery, Inc
Intravenous sedation for the closed reduction of fractures in children
CD Varela, KC Lorfing and TL Schmidt
Department of Orthopaedic Surgery, Children's Mercy Hospital, Kansas City 64108.
The safety and efficacy of intravenous sedation with both a narcotic and a
benzodiazepine were evaluated in 104 consecutive children who had closed
reduction of a fracture. Six patients had a subsequent additional reduction
with intravenous sedation, so the study involved a total of 110 procedures.
The average dose of meperidine was 1.47 milligrams per kilogram of body
weight, and the average dose of midazolam was 0.11 milligram per kilogram
of body weight. The interval between induction of the sedation and
performance of the procedure averaged ten minutes, and the total duration
of the procedure averaged thirty-nine minutes. There were no episodes of
apnea or cardiorespiratory complications. Ninety-six (92 percent) of the
initial 104 reductions were successful. Only four patients subsequently
needed general anesthesia for a repeat closed reduction. The physician's
satisfaction with the method of sedation was good or excellent for 103 (94
per cent) of the 110 procedures. Eighty-one (93 per cent) of eighty-seven
patients who were able to respond had no memory of the reduction. A
telephone survey conducted after the procedure revealed that eighty-four
(98 per cent) of eighty-six parents who responded were satisfied with the
method of sedation. Intravenous sedation with a narcotic and a
benzodiazepine proved to be a safe and effective method of anesthesia for
the closed reduction of fractures in children in our series. Careful
monitoring of the patient after sedation is imperative.