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The Journal of Bone and Joint Surgery, Vol 76, Issue 3 341-348, Copyright © 1994 by Journal of Bone and Joint Surgery, Inc
The prevalence of deep venous thrombosis after total hip arthroplasty with hypotensive epidural anesthesia
JR Lieberman, MM Huo, J Hanway, EA Salvati, TP Sculco and NE Sharrock
Hospital for Special Surgery, New York, NY 10021.
A prospective, randomized trial was done to evaluate the prevalence of deep
venous thrombosis following primary unilateral or bilateral total hip
arthroplasty with use of hypotensive epidural anesthesia, external
pneumatic-compression boots, and aspirin (Group I) and with use of
hypotensive epidural anesthesia and aspirin (Group II). All operations were
performed by two of us (E. A. S. and T. P. S.) through a posterolateral
approach. Two hundred and thirty-one patients who were more than
thirty-nine years old and who had a total of 250 primary total hip
arthroplasties were included in the study. There were 113 patients (124
hips) in Group I and 118 patients (126 hips) in Group II. All patients had
venography on the sixth, seventh, or eighth postoperative day. Group I had
no proximal thrombi, seven distal thrombi (6 per cent), and one late
pulmonary embolus (1 per cent). Group II had one proximal thrombus
(popliteal) (1 per cent), eight distal thrombi (6 per cent), and one late
pulmonary embolus (1 per cent). The difference was not significant (p =
0.65). However, a significant difference may have been noted if the study
population had been larger. The combination of hypotensive epidural
anesthesia and aspirin is effective prophylaxis against deep venous
thrombosis in patients who have a primary total hip arthroplasty. The
extremely low rate of deep venous thrombosis in the present study may be
attributed to the use of hypotensive epidural anesthesia and the associated
decrease in blood loss and transfusion requirements.(ABSTRACT TRUNCATED AT
250 WORDS)

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